白细胞介素-6与急性时相蛋白：抗炎和免疫抑制介质。
IL-6 and APPs: anti-inflammatory and immunosuppressive mediators.
作者信息
Tilg H, Dinarello C A, Mier J W
机构信息
Dept of Medicine, University Hospital Innsbruck, Austria.
出版信息
Immunol Today. 1997 Sep;18(9):428-32. doi: 10.1016/s0167-5699(97)01103-1.
PMID:9293158
Abstract
Acute inflammation is accompanied by changes in the concentrations of acute phase proteins (APPs). While much is known about the cytokines involved in the initiation of inflammation, less is known about the mediators involved in its resolution. Recent data suggest that interleukin 6 (IL-6) and IL-6-regulated APPs are anti-inflammatory and immuno-suppressive, and may negatively regulate the acute phase response.
摘要
急性炎症伴随着急性期蛋白（APPs）浓度的变化。虽然人们对参与炎症起始的细胞因子了解很多，但对参与炎症消退的介质了解较少。最近的数据表明，白细胞介素6（IL-6）和IL-6调节的APPs具有抗炎和免疫抑制作用，可能对急性期反应产生负调节作用。
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