Vicaretti M, Fletcher J P, Klineberg P, Richardson A J, Hazelton S, Allen R, Tomlinson P, Nunn G, Chard R, Meldrum-Hanna W
Division of Surgery, Westmead Hospital, NSW, Australia.
Cardiovasc Surg. 1997 Jun;5(3):266-70. doi: 10.1016/s0967-2109(97)00017-3.
Combined carotid endarterectomy and coronary artery bypass grafting was performed in 52 patients between January 1982 and September 1994. Forty-nine patients had stable or unstable angina and three had symptom-free coronary artery disease detected by stress testing. Thirty-one patients had triple-vessel disease and 17 had left main trunk or left main equivalent coronary artery disease. Five patients had symptom-free carotid artery disease, 12 had non-specific neurological symptoms, and 35 had transient ischaemic attacks. Carotid endarterectomy was performed first, followed by coronary artery bypass grafting. There were three postoperative deaths, two cardiac and one neurological, for a mortality rate of 5.8%. One patient suffered a permanent neurological deficit (1.9%). It is concluded that combined carotid endarterectomy/coronary artery bypass grafting can be performed in selected patients with acceptable neurological morbidity, although cardiac mortality was not eliminated by the combined approach.
1982年1月至1994年9月期间,对52例患者实施了颈动脉内膜切除术和冠状动脉旁路移植术联合手术。49例患者患有稳定型或不稳定型心绞痛,3例通过负荷试验检测出无症状性冠状动脉疾病。31例患者患有三支血管病变,17例患有左主干或左主干等同冠状动脉疾病。5例患者患有无症状性颈动脉疾病,12例有非特异性神经症状,35例有短暂性脑缺血发作。先进行颈动脉内膜切除术,然后进行冠状动脉旁路移植术。术后有3例死亡,2例死于心脏原因,1例死于神经原因,死亡率为5.8%。1例患者出现永久性神经功能缺损(1.9%)。结论是,对于选定的患者,尽管联合手术未能消除心脏死亡率,但颈动脉内膜切除术/冠状动脉旁路移植术联合手术可以在可接受的神经并发症发生率下进行。