Metintaş M, Alataş O, Alataş F, Colak O, Ozdemir N, Erginel S
Department of Chest Diseases, Osmangazi University Medical Faculty, Eskişehir, Turkey.
Clin Chim Acta. 1997 Aug 29;264(2):149-62. doi: 10.1016/s0009-8981(97)00091-0.
The differentiation of pleural effusions as being either transudate or exudate is the first step in the diagnosis of pleural effusions. The aim of this study was to compare the efficiency of the various biochemical parameters to the traditional criteria of Light et al., for differentiating exudates from transudates. Ninety-three pleural fluid and sera specimens were obtained and classified as transudates or exudates on the basis of their diagnosis. Of the 93 pleural fluids, 21 were transudates, 72 were exudates. The efficiencies of different parameters for detection of exudates were as follows: The criteria of Light 96%; effusion cholesterol concentration 77%; serum-fluid albumin gradient 67%, pleural/serum alkaline phosphatase ratio 83%; effusion creatine kinase levels 91%; pleural/serum creatine kinase ratio 83%, and effusion uric acid 71%. Pleural/serum uric acid ratio was insignificant for the purpose of this study.
鉴别胸腔积液是漏出液还是渗出液是胸腔积液诊断的第一步。本研究的目的是比较各种生化参数与Light等人的传统标准在鉴别渗出液和漏出液方面的效率。获取了93份胸水和血清标本，并根据诊断将其分类为漏出液或渗出液。在93份胸水中，21份为漏出液，72份为渗出液。不同参数检测渗出液的效率如下：Light标准为96%；胸水胆固醇浓度为77%；血清-胸水白蛋白梯度为67%，胸水/血清碱性磷酸酶比值为83%；胸水肌酸激酶水平为91%；胸水/血清肌酸激酶比值为83%，以及胸水尿酸为71%。胸水/血清尿酸比值在本研究中无显著意义。
