抗真菌药物耐药性的最新情况。
Update on antifungal resistance.
作者信息
Klepser M E, Ernst E J, Pfaller M A
机构信息
University of Iowa College of Pharmacy, Iowa City 52242, USA.
出版信息
Trends Microbiol. 1997 Sep;5(9):372-5. doi: 10.1016/S0966-842X(97)01108-6.
PMID:9294895
Abstract
Overuse of antifungal agents has resulted in the selection of naturally resistant Candida species, as well as expression of resistance from previously susceptible species resulting from genetic mutations and/or selection of resistant subpopulations. Strategies for the appropriate use of antifungal agents need to be developed to prevent further development of resistance.
摘要
抗真菌药物的过度使用导致了天然耐药念珠菌属的出现，以及先前敏感菌种因基因突变和/或耐药亚群的选择而产生耐药性。需要制定合理使用抗真菌药物的策略，以防止耐药性的进一步发展。
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