Lisek E W, Levine L A
Department of Urology, Rush-Presbyterian St. Luke's Medical Center, Chicago, Illinois 60612, USA.
Tech Urol. 1997 Summer;3(2):81-5.
Percutaneous sperm aspiration from the epididymis (PESA) or testicle (TESA) may be used as a diagnostic technique to confirm sperm production and as a method to harvest sperm for use in intracytoplasmic sperm injection (ICSI). We performed 43 PESA/TESA procedures in men considered to have nonreconstructible obstructive azoospermia. This short outpatient procedure was performed using a butterfly needle under intravenous i.v. sedation and local anesthesia. In 17 diagnostic aspirations, diagnoses of normal spermatogenesis, maturation arrest, and germ cell aplasia were established. In 26 therapeutic sperm aspirations for use with ICSI, adequate samples of sperm were obtained and residual sperm was cryopreserved. In the ICSI cycles, fertilization and pregnancy rates of 59% and 32%, respectively, were obtained. PESA/TESA is a minimally invasive sperm retrieval technique and appears to be an effective alternative to microsurgical epididymal sperm aspiration, which is more invasive, costly, and technically more difficult. There have been no acute or chronic complications in this patient population, including nine men who underwent a second successful procedure.
经皮附睾精子抽吸术（PESA）或睾丸精子抽吸术（TESA）可用作一种诊断技术，以确认精子生成情况，也可作为获取精子用于胞浆内单精子注射（ICSI）的一种方法。我们对被认为患有不可重建性梗阻性无精子症的男性患者进行了43例PESA/TESA手术。该门诊短程手术是在静脉镇静和局部麻醉下使用蝶形针进行的。在17例诊断性抽吸中，确定了正常精子发生、成熟停滞和生殖细胞发育不全的诊断。在26例用于ICSI的治疗性精子抽吸中，获得了足够的精子样本，并将剩余精子冷冻保存。在ICSI周期中，受精率和妊娠率分别为59%和32%。PESA/TESA是一种微创性精子获取技术，似乎是显微外科附睾精子抽吸术的一种有效替代方法，后者具有更强的侵入性、成本更高且技术难度更大。在该患者群体中未出现急性或慢性并发症，包括9例接受了第二次成功手术的男性患者。
