Dimitrov K
Vet Med Nauki. 1977;14(5):55-60.
The comparative testing of the immunogenic activity of vaccines produced with strain K cultured in cell cultures and rabbits has revealed that one vaccinal dose of the culture vaccine for pigs contains 1 000 reactogenic doses for rabbits and about 400 immunizing doses for pigs. In a vaccinal dose for pigs of a vaccine obtained from rabbits there are 400 reactogenic doses for rabbits and 100 immunizing doses for pigs. Swine fever-affected pigs treated with a vaccine of strain K, containing more than 100 immunizing doses per vaccinal dose, develop immunity that lasts not less than 12 months. Freeze-dried vaccines of strain K can be stored at ordinary refrigerator temperature in the course of one year, and at minus 20 to 30 degrees C--in the course of two years.
对在细胞培养物和兔体中培养的K株疫苗免疫原活性进行的对比测试表明，猪用培养疫苗的一个疫苗剂量含有对兔的1000个反应原剂量和约对猪的400个免疫剂量。从兔体获得的疫苗在猪用疫苗剂量中含有对兔的400个反应原剂量和对猪的100个免疫剂量。用每疫苗剂量含有超过100个免疫剂量的K株疫苗治疗的猪瘟感染猪产生的免疫力持续不少于12个月。K株冻干疫苗可在普通冰箱温度下保存一年，在零下20至30摄氏度下保存两年。
