Dimitrov K
Vet Med Nauki. 1976;13(1):59-62.
Investigated was the amount of the immunizing doses per one vaccinal pig dose of five operative numbers of the lapinized K vaccine against swine fever. For this purpose pigs were immunized with 100, 200, 300, 400, and 500 fold dilutions of the vaccinal dose. A couple of weeks later the pigs were infected with 10(6)LD50 each of a pathogenic swine fever virus. It was found that the immunizing doses for the individual operative numbers of the vaccine vary in number from 100 to 400 in one vaccinal dose.
研究了猪瘟兔化K疫苗五个生产批次每头份疫苗的免疫剂量。为此,用疫苗剂量的100倍、200倍、300倍、400倍和500倍稀释液对猪进行免疫。几周后,每头猪用10(6)LD50的致病性猪瘟病毒进行感染。结果发现,疫苗各生产批次每头份的免疫剂量在100至400之间不等。