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伏隔核与学习和记忆。

The nucleus accumbens and learning and memory.

作者信息

Setlow B

机构信息

Department of Psychobiology and Center for the Neurobiology of Learning and Memory, University of California, Irvine 92697-3800, USA.

出版信息

J Neurosci Res. 1997 Sep 1;49(5):515-21. doi: 10.1002/(SICI)1097-4547(19970901)49:5<515::AID-JNR1>3.0.CO;2-E.

Abstract

Recent research on the nucleus accumbens (NA) indicates that this brain region is involved in learning and memory processes in a way that is separable from its other well-known roles in behavior, such as motivation, reward, and locomotor activity. These findings have suggested that 1) the NA may be involved in declarative, or hippocampal formation-dependent learning and memory, and not in several other non-declarative forms of learning and memory, and 2) the NA may be selectively involved in certain stages of learning and memory. These characteristics suggest that the NA may be part of a larger striatal system which subserves acquisition and consolidation, but is not a site of long-term storage, of different forms of learning and memory.

摘要

最近对伏隔核(NA)的研究表明,该脑区参与学习和记忆过程的方式,与它在行为中其他广为人知的作用(如动机、奖赏和运动活动)是可分离的。这些发现表明:1)伏隔核可能参与陈述性记忆,即依赖海马体形成的学习和记忆,而不参与其他几种非陈述性学习和记忆形式;2)伏隔核可能选择性地参与学习和记忆的某些阶段。这些特征表明,伏隔核可能是一个更大的纹状体系统的一部分,该系统有助于不同形式学习和记忆的获取和巩固,但不是长期存储的部位。

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