Wortley P M, Fleming P L
Division of HIV/AIDS Prevention, National Centers for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Ga 30333, USA.
JAMA. 1997 Sep 17;278(11):911-6.
The effect of the acquired immunodeficiency syndrome (AIDS) epidemic on women is substantial and warrants an updated analysis.
To describe AIDS incidence trends in women.
We analyzed national surveillance data on women 13 years of age and older with AIDS reported through June 1996. Data were adjusted for reporting delay, unreported risk, and the 1993 change in AIDS surveillance case definition to assess overall trends and examine trends by age group and birth cohort.
Surveillance conducted by the Centers for Disease Control and Prevention in collaboration with state and local health departments.
In 1995, women accounted for 19% of AIDS cases in adults; AIDS incidence rates per 100000 women were highest in black women (50.1), women in the Northeast (22.3), heterosexual contacts (5.5), and women living in metropolitan statistical areas with more than 1 million residents (15.9). Greatest increases in rates between 1991 and 1995 by region and mode of transmission were in the South and in heterosexual contacts. Greatest increases in AIDS incidence rates were observed in heterosexually infected women born between 1970 and 1974, ie, women who were 14 to 18 years old in 1988.
These trends predict continued growth of the number of AIDS cases in women, especially in those in the South and those infected heterosexually, and suggest that successive cohorts of young women may be at risk for human immunodeficiency virus infection as they reach adolescence and young adulthood. Prevention programs must reach young women before they initiate sexual activity and drug use.
获得性免疫缺陷综合征(艾滋病)流行对女性的影响巨大,值得进行更新分析。
描述女性艾滋病发病率趋势。
我们分析了截至1996年6月报告的13岁及以上艾滋病女性患者的国家监测数据。对报告延迟、未报告风险以及1993年艾滋病监测病例定义的变化进行了数据调整,以评估总体趋势并按年龄组和出生队列研究趋势。
疾病控制和预防中心与州及地方卫生部门合作进行的监测。
1995年,女性占成人艾滋病病例的19%;每10万名女性中的艾滋病发病率在黑人女性中最高(50.1),东北部女性中(22.3),异性接触者中(5.5),以及居住在人口超过100万的大都市统计区的女性中(15.9)。1991年至1995年间,按地区和传播方式划分的发病率增幅最大的是南部地区和异性接触者。艾滋病发病率增幅最大的是1970年至1974年出生的异性感染女性,即在1988年年龄为14至18岁的女性。
这些趋势预示着女性艾滋病病例数将持续增加,尤其是南部地区的女性和异性感染的女性,并表明年轻女性的连续队列在进入青春期和年轻成年期时可能面临感染人类免疫缺陷病毒的风险。预防项目必须在年轻女性开始性行为和吸毒之前开展。