Zharinov O I, Panasiuk Ie M, Ivaniv Iu A, Pavliuk V I
Fiziol Zh (1994). 1997;43(3-4):130-3.
The Doppler method makes possible to reveal the relaxation disturbances and the increased left ventricular (LV) stiffness-pathophysiologic mechanisms of diastolic myocardial dysfunction (DMD), exerting opposite influence on the correlation of transmitral flow peaks. The decrease of the "diastolic reserve" in the patients with lung congestion is useful to diagnose DMD. But the type of LV filling, when the relative role of early diastole is decreased and of the late diastole-increased, cannot itself be recognized as pathologic. From the other side, the normal transmitral flow graphics doesn't allow to exclude DMD completely. The interpretation of Doppler parameters must take into consideration other factors influencing the LV diastolic filling: preload, systolic dysfunction and mitral regurgitation.
多普勒方法能够揭示舒张期心肌功能障碍（DMD）的舒张期干扰及左心室（LV）僵硬度增加的病理生理机制，这些机制对二尖瓣血流峰值的相关性产生相反影响。肺淤血患者“舒张期储备”的降低有助于诊断DMD。但是，当舒张早期的相对作用降低而舒张晚期的相对作用增加时，LV充盈类型本身不能被视为病理性的。另一方面，正常的二尖瓣血流图形并不能完全排除DMD。对多普勒参数的解释必须考虑影响LV舒张期充盈的其他因素：前负荷、收缩功能障碍和二尖瓣反流。
