Carbajal J A, Villar J, Lanuza M D, Esteban J G, Muñoz C, Borrás R
Departamento de Microbiología, Facultad de Medicina y Hospital Clínico Universitario, Valencia.
Med Clin (Barc). 1997 Apr 26;108(16):608-12.
To evaluate the frequency of Blastocystis hominis parasitation and to ascertain its role as an intestinal a prospective study during 18 months pathogen has been carried out.
The study included 2,039 patients, which were classified in three groups (asymptomatic [group A], with suspicion of parasitosis [group B], with diarrhoea [group C]). In all cases a coproparasitological study was performed. In the group C the presence of non-parasitic enteropathogens was also investigated. In patients with B. hominis in the absence of other pathogens clinical and epidemiological characteristics were evaluated. Also, its was determined the morphology and quantification of parasites.
Parasites were identified in 26.2% of population. B. hominis was identified in 336 patients (16.5%). The frequency of parasitation was superior in adults (p < 0.0001), with a slight predominance in the female sex. The rate of asymptomatic carriers was 3.3%. In 21 patients B. hominis (group C) was observed in absence of other enteropathogens. Statistical significant association was found between B. hominis, in absence of other pathogens and the presence of clinical manifestations (p < 0.0001), the most common of which were diarrhoea and abdominal pain. We did not find a statistically significant association between the number of B. hominis present and stool characteristics. The vacuolar form was the predominant morphological type. The ameboid form was observed only in diarrhoeal stools.
B. hominis is the most frequent parasite found in faecal parasitological investigation. In absence of other causes, B. hominis must be considered as a pathogen.
为评估人芽囊原虫寄生的频率并确定其作为肠道病原体的作用，开展了一项为期18个月的前瞻性研究。
该研究纳入2039例患者，分为三组（无症状组[A组]、疑似寄生虫感染组[B组]、腹泻组[C组]）。所有病例均进行了粪便寄生虫学研究。C组还调查了非寄生虫性肠道病原体的存在情况。对于无人芽囊原虫以外其他病原体的患者，评估其临床和流行病学特征。此外，还确定了寄生虫的形态和数量。
在26.2%的人群中发现了寄生虫。336例患者（16.5%）检测出人芽囊原虫。成年人中的寄生频率更高（p<0.0001），女性略占优势。无症状携带者的比例为3.3%。在21例患者（C组）中，未发现其他肠道病原体，仅检测出人芽囊原虫。在无人芽囊原虫以外其他病原体的情况下，人芽囊原虫与临床表现之间存在统计学显著关联（p<0.0001），最常见的临床表现为腹泻和腹痛。我们未发现人芽囊原虫数量与粪便特征之间存在统计学显著关联。空泡型是主要的形态类型。仅在腹泻粪便中观察到阿米巴样形态。
人芽囊原虫是粪便寄生虫学调查中最常见的寄生虫。在无其他病因的情况下，人芽囊原虫必须被视为病原体。
