[Conditioned reflex mechanism in the hypothalamic regulation of diuresis].

In chronic experiments on dogs with urethrae brought out to the skin of the abdomen and electrodes implanted in the hypothalamus, the possibility was studied of the involvement of a conditioned component in hypothalamic control of the kidneys activity under a direct action of electric current on a hypothalamus. The beat of a metronome and the experimental surroundings served as a conditioned stimulus, stimulation of the hypothalamus was used as an unconditioned one, and diuresis -- as a manifestation of the conditioned reflex. It was found that the conditioned mechanism is also involved in the complex mechanism of hypothalamic control of kidney activity. Such conditioned changes of diuresis may be effected in different functional states of hypothalamic nuclei.