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[犬对下丘脑电刺激的工具性防御性条件反射]

[Instrumental defensive conditioned reflexes to electric stimulation of the hypothalamus in dogs].

作者信息

Chilingarian L I, Gurskaia I E

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1981 Jul-Aug;31(4):684-94.

PMID:7303893
Abstract

An instrumental defensive conditioned reflex to electrical stimulation of the lateral hypothalamus (LHS) was elaborated in seven dogs with electrodes implanted in different structures of the limbic system. Electrocutaneous stimulation was disrupted by a lift of the foreleg to a certain level. The conditioned reflex developed slowly: it appeared at the 15th to 35 th pairing, became stable by the 120--150th pairing of stimuli and reached a 60--90% level. Extinction of the conditioned reflex took 70--80 presentations of the conditioned stimulus without reinforcement. As LHS turned into a signal of electrocutaneous stimulation, the typical reactions to it weakened; in particular, searching movements and sniffing virtually disappeared, while licking movements appeared much more seldom both during the action of the conditioned stimulus and in the intervals between stimuli pairings.

摘要

在七只狗身上建立了对下丘脑外侧(LHS)电刺激的工具性防御条件反射,这些狗的电极植入了边缘系统的不同结构。前肢抬起至一定高度会干扰皮肤电刺激。条件反射发展缓慢:在第15至35次配对时出现,在第120至150次刺激配对时变得稳定,并达到60%至90%的水平。条件反射的消退需要在无强化情况下对条件刺激进行70至80次呈现。随着LHS变成皮肤电刺激的信号,对其的典型反应减弱;特别是,搜寻动作和嗅闻几乎消失,而舔舐动作在条件刺激作用期间和刺激配对间隔期间出现的频率也大大降低。

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