宫颈分泌物中的胎儿纤维连接蛋白可准确预测足月分娩的开始。
Fetal fibronectin in the cervical secretion predicts accurately the onset of labor at term.
作者信息
Luton D, Guibourdenche J, Sibony O, Braig S, Benzakine Y, Oury J F, Porquet D, Blot P
机构信息
Service de Maternité, Hôpital Robert-Debré, Paris, France.
出版信息
Eur J Obstet Gynecol Reprod Biol. 1997 Aug;74(2):161-4. doi: 10.1016/s0301-2115(97)00109-7.
OBJECTIVE
The objective of our study was to check if presence of fetal fibronectin in the cervical secretion of full term patient predicts accurately the onset of labour at term.
STUDY DESIGN
78 women in the term period were included in the study, serial samples for fetal fibronectin were assessed, each patient underwent spontaneous labour, delay between last sample and delivery were analysed.
RESULTS
Patient with positive fetal fibronectin delivered within 3 +/- 1.9 days where as patient with negative fetal fibronectin delivered within 5.7 +/- 3.9 days (P = 0.01).
CONCLUSION
Presence of fetal fibronectin in cervical secretions seems to be a powerful tool to predict in a short delay the onset of labour at term, it should be used in conjunction with clinical and fetal assessment data.
目的
我们研究的目的是检查足月患者宫颈分泌物中胎儿纤连蛋白的存在是否能准确预测足月分娩的开始。
研究设计
78名足月孕妇被纳入研究，对胎儿纤连蛋白进行系列样本评估，每位患者均经历自然分娩，分析最后一次采样与分娩之间的间隔时间。
结果
胎儿纤连蛋白呈阳性的患者在3±1.9天内分娩，而胎儿纤连蛋白呈阴性的患者在5.7±3.9天内分娩（P = 0.01）。
结论
宫颈分泌物中存在胎儿纤连蛋白似乎是一种能在短期内预测足月分娩开始的有力工具，应结合临床和胎儿评估数据使用。
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