Jackson T, Ditmanson L, Phibbs B
College of Medicine, University of Arizona, Tucson, USA.
Arch Intern Med. 1997 Sep 22;157(17):2013-5.
Haloperidol, used to treat patients with psychoses, is considered minimally cardiotoxic. Several cases of torsade de pointes have been reported in association with the use of oral haloperidol. In each of those cases, a prolonged QTc preceded the torsade de pointes episode and thus may be considered a predictor for ventricular arrhythmias in elderly women treated with haloperidol. However, the following case may demonstrate the inability to predict an episode of torsade de pointes with low-dose oral haloperidol use.
用于治疗精神病患者的氟哌啶醇被认为心脏毒性极小。有几例尖端扭转型室速的病例报告与口服氟哌啶醇的使用有关。在每一例此类病例中，尖端扭转型室速发作前均有QTc延长，因此可被视为使用氟哌啶醇治疗的老年女性室性心律失常的一个预测指标。然而，以下病例可能表明无法预测低剂量口服氟哌啶醇时发生的尖端扭转型室速发作。
