Lewis B A, Freebairn L
Department of Pediatrics, School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
J Commun Disord. 1997 Sep-Oct;30(5):385-401; quiz 401-2. doi: 10.1016/s0021-9924(96)00110-4.
Familial aggregation of speech and language disorders was examined as a basis of subgrouping children with phonologic disorders. Fifty-nine children with phonologic disorders were subgrouped according to whether or not other nuclear family members reported a history of speech/language disorders. Thirty-four subjects (58%) reported at least one other nuclear family member affected and 25 subjects (42%) reported no other nuclear family members affected. Groups were compared on measures of articulation, phonology, language, and oral motor skills to determine if the familial phonologic subgroup presented a unique profile of speech and language deficits. Significant group differences were not observed. However, children with positive nuclear family histories tended to perform more poorly than children without histories on all tasks, although not reaching significance. Although all parents were considered to have achieved normal adult articulation, parents of children with positive family histories also tended to perform more poorly than parents of children with negative histories. Results suggested that poorer oral motor coordination and productive phonology may distinguish individuals with familial phonologic disorders from individuals with phonologic disorders of unknown origin.
作为对患有音韵障碍儿童进行亚组划分的依据，我们对言语和语言障碍的家族聚集性进行了研究。59名患有音韵障碍的儿童根据其他核心家庭成员是否报告有言语/语言障碍病史进行了亚组划分。34名受试者（58%）报告至少有一名其他核心家庭成员受到影响，25名受试者（42%）报告没有其他核心家庭成员受到影响。对两组在发音、音韵、语言和口腔运动技能方面的指标进行比较，以确定家族性音韵亚组是否呈现出独特的言语和语言缺陷特征。未观察到显著的组间差异。然而，有阳性核心家族史的儿童在所有任务上的表现往往比没有家族史的儿童更差，尽管未达到显著水平。尽管所有父母都被认为已达到正常的成人发音水平，但有阳性家族史儿童的父母表现也往往比有阴性家族史儿童的父母更差。结果表明，较差的口腔运动协调性和产出性音韵能力可能是患有家族性音韵障碍的个体与病因不明的音韵障碍个体之间的区别所在。
