Seeber A, Blaszkewicz M, Golka K, Kiesswetter E
Institute of Occupational Health, University of Dortmund, Dortmund, 44139, Germany.
Environ Res. 1997;73(1-2):81-91. doi: 10.1006/enrs.1997.3711.
Ratings on analog scales for dimensions of well-being provide information about the acute state of well-being during solvent exposure. In a study of volunteers and workers exposed to solvents, tension, tiredness, complaints, and annoyance were rated on seven-point scales. Dose-effect relationships were analyzed for several scenarios; data were collected in diaries during work hours. In two studies, 40 volunteers in an exposure laboratory were exposed to ethanol by inhalation at levels between 80 and 1900 parts per million (ppm). In two other studies, 32 volunteers were exposed to acetone and ethyl acetate in single exposures (1000 and 500 ppm, respectively) and combined exposures (500 ppm acetone + 200 ppm ethyl acetate). A field study of 8 exposed workers and 8 nonexposed controls involved exposures of up to 2100 ppm acetone. Dose-effect relationships were shown for ratings of annoyance by correlations of 0.36 (ethanol) and 0.58 (acetone). Similar coefficients were found for ratings of complaints. The dimensions tension and tiredness showed no stable relationship with exposure. The consistency of ratings was assessed by means of correlations between the ratings given during periods of nearly equal exposures. Ratings of annoyance for the different studies between the periods of nearly equal exposure showed average correlations from 0.68 to 0.84. For the ratings of complaints, the coefficients were 0.53 to 0.81. The coefficients for tension had similar stabilities; those for tiredness were lower.
幸福维度的模拟量表评分提供了溶剂暴露期间幸福的急性状态信息。在一项针对接触溶剂的志愿者和工人的研究中，紧张、疲劳、不适和烦恼程度用七点量表进行评分。分析了几种情况下的剂量 - 效应关系；数据在工作时间的日记中收集。在两项研究中，暴露实验室的40名志愿者通过吸入接触百万分之80至1900（ppm）的乙醇。在另外两项研究中，32名志愿者分别单次接触丙酮和乙酸乙酯（分别为1000 ppm和500 ppm）以及联合接触（500 ppm丙酮 + 200 ppm乙酸乙酯）。一项针对8名暴露工人和8名未暴露对照的现场研究涉及高达2100 ppm丙酮的暴露。烦恼评分的剂量 - 效应关系通过0.36（乙醇）和0.58（丙酮）的相关性显示。抱怨评分也发现了类似的系数。紧张和疲劳维度与暴露没有显示出稳定的关系。评分的一致性通过几乎相等暴露期间给出的评分之间的相关性来评估。几乎相等暴露期间不同研究的烦恼评分显示平均相关性在0.68至0.84之间。对于抱怨评分，系数为0.53至0.81。紧张评分的系数具有类似的稳定性；疲劳评分的系数较低。
