Kiesswetter E, Seeber A, Golka K, Sietmann B
Institute für Arbeitphysiologie an der Universität Dortmund, Ardeystr. 67, 44139 Dortmund, Germany.
Int J Occup Environ Health. 1997 Jul;3(Supplement 2):S61-S66.
The effects of different conditions of occupational exposure to organic solvents on subjective sleep quality were studied with and without shiftwork. Laboratory studies showed that four hours of daytime exposure to ethanol (400, 800 ppm) by inhalation led to blood ethanol levels below 0.01 per thousand and had marginal effects on the following night's sleep. Exposures to acetone (1,000 ppm), ethyl acetate (400 ppm), and a solvent mixture (acetone 500 ppm, ethyl acetate 200 ppm) increased the subjective depth of sleep. In a field study with eight hours of exposure, during three different work shifts, dose-response relationships between acetone concentrations during the shiftwork and the depth of sleep were found. Nevertheless, the solvent-exposed shift workers reported a reduced sleep quality, mainly in connection with daytime sleep, in comparison with non-exposed shift workers. The effects of solvent exposure during shiftwork on sleep varied with time of day of the exposure.
研究了有无轮班工作情况下，不同职业接触有机溶剂条件对主观睡眠质量的影响。实验室研究表明，白天吸入乙醇4小时（400、800 ppm）会使血液乙醇水平低于千分之一，且对随后夜晚的睡眠影响甚微。接触丙酮（1000 ppm）、乙酸乙酯（400 ppm）和一种溶剂混合物（丙酮500 ppm、乙酸乙酯200 ppm）会增加主观睡眠深度。在一项为期8小时接触的现场研究中，在三个不同工作班次期间，发现了轮班工作期间丙酮浓度与睡眠深度之间的剂量反应关系。然而，与未接触溶剂的轮班工人相比，接触溶剂的轮班工人报告睡眠质量下降，主要与白天睡眠有关。轮班工作期间接触溶剂对睡眠的影响随接触时间的不同而变化。
