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[细胞遗传学研究在犬类白血病中的重要性]

[Importance of cytogenetic investigations in canine leukemias].

作者信息

Nolte I, Reimann N, Bullerdiek J, Bartnitzke S, Mischke R, Nolte M

机构信息

Klinik für kleine Haustiere, Tierärztlichen Hochschule Hannover.

出版信息

Tierarztl Prax. 1997 Jul;25(4):393-7.

PMID:9312901
Abstract

Like in man, in neoplastic haematopoietic diseases of the dog genetical changes can be detected cytogenetically. In this study, some cytogenetically characterized cases are presented and discussed against the background of comparable cases reported in the literature. In two out of three patients investigated, one or two extra copies of chromosome 1 were detected. Corresponding changes have also been described in two other cases in the literature.

摘要

与人类一样,在犬类的肿瘤性造血疾病中,可以通过细胞遗传学检测到基因变化。在本研究中,呈现了一些经细胞遗传学特征化的病例,并结合文献中报道的类似病例进行讨论。在三名接受调查的患者中,有两名检测到1号染色体多了一两条拷贝。文献中另外两个病例也描述了相应的变化。

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