Borrego M, Pimentel D, Rebelo I
Departamento de Radioterapia, I.P.O.F.G., Coimbra.
Acta Med Port. 1997 May;10(5):367-71.
From December 1965 to December 1987 (22 years), 279 patients with histologically confirmed squamous cell carcinoma of the lip were treated in this Department with roentgenotherapy. All the patients that had completed the treatment were evaluated with a follow-up time of 5 years (n = 255). Distribution by age, sex, occupation, residence, evolution time of the lesion, localization (upper lip, lower lip and commissure), tumor size and histological grade were analysed. In what concerns technical conditions and fractionation, we evaluated the type of acute reactions and the dose of radiation which elicited them as well as the results of radiotherapy (local and cosmetic control). A relation is made between the size of the lesion and outcome after treatment. The survival rate at 3 years was 76.6% and at 5 years (the usual follow-up period for these patients) 66%. Disease-free survival rate at 3 years was 79% and at 5 years 77.6%.
1965年12月至1987年12月（22年）期间，本科室对279例经组织学确诊的唇鳞状细胞癌患者进行了放射治疗。所有完成治疗的患者均接受了5年的随访评估（n = 255）。分析了患者的年龄、性别、职业、居住地、病变发展时间、病变部位（上唇、下唇和口角）、肿瘤大小和组织学分级。在技术条件和分割方式方面，我们评估了急性反应的类型及其引发剂量，以及放射治疗的结果（局部控制和美容效果）。分析了病变大小与治疗后结果之间的关系。3年生存率为76.6%，5年生存率（这些患者的常规随访期）为66%。3年无病生存率为79%，5年无病生存率为77.6%。
