Borrego M, Pimentel D, Rebelo I
Departamento de Radioterapia, I.P.O.F.G. Coimbra.
Acta Med Port. 1997 Jan;10(1):47-51.
From December 1965 to December 1987 (22 years), 279 patients with histologically confirmed squamous cell carcinoma of the lip were treated in this Department with roentgenotherapy. All the patients that had completed the treatment were evaluated with a follow-up time of 5 years (n=255). Distribution by age, sex, occupation, residence, evolution time of the lesion, localization (upper lip, lower lip and commissure), tumoral size and histological grade were analysed. Concerning technical conditions and fractionation, we evaluated the type and which dose of radiation elicit acute reactions as well as the results of radiotherapy (local and cosmetic control). A relation is made between the size of the lesion and outcome after treatment. The survival rate at 3 years was 76,6% and at 5 years (the usual follow-up period for these patients) was 66%. Disease-free survival rate at 3 years was 79% and at 5 years was 77,6%.
1965年12月至1987年12月（共22年），本科室对279例经组织学确诊的唇鳞状细胞癌患者进行了放射治疗。所有完成治疗的患者均进行了评估，随访时间为5年（n = 255）。分析了患者的年龄、性别、职业、居住地、病变发展时间、病变部位（上唇、下唇和口角）、肿瘤大小及组织学分级。关于技术条件和分割方式，我们评估了引发急性反应的放射类型和剂量以及放射治疗结果（局部控制和美容效果）。分析了病变大小与治疗后结局之间的关系。3年生存率为76.6%，5年生存率（这些患者的常规随访期）为66%。3年无病生存率为79%，5年无病生存率为77.6%。
