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男性心肌梗死后的功能恢复:社会阶层的独立影响。

Functional recovery after myocardial infarction in men: the independent effects of social class.

作者信息

Ickovics J R, Viscoli C M, Horwitz R I

机构信息

Department of Internal Medicine, Yale University, New Haven, CT 06520-8025, USA.

出版信息

Ann Intern Med. 1997 Oct 1;127(7):518-25. doi: 10.7326/0003-4819-127-7-199710010-00003.

Abstract

BACKGROUND

Social class has been repeatedly associated with cardiovascular-related illness and death, but no studies have examined the effect of social class on recovery from myocardial infarction. Moreover, few studies have simultaneously evaluated a broad array of f1p4graphic, clinical, and psychosocial factors that may influence health outcomes after myocardial infarction.

OBJECTIVE

To determine whether social class remains independently associated with functional recovery after myocardial infarction, even after controlling for clinical, demographic, and psychosocial factors known to influence outcomes after infarction.

DESIGN

Analysis of prospective data from a multicenter, randomized, double-blind clinical trial.

SETTING

25 hospitals or clinical settings in the United States and Canada that participated in the Beta Blocker Heart Attack Trial, including the Health Insurance Plan substudy.

PATIENTS

2145 men 29 to 69 years of age who were hospitalized with acute myocardial infarction and were recruited into the Beta Blocker Heart Attack Trial.

MEASUREMENTS

The primary outcome was change in New York Heart Association functional class between baseline assessment and 12 months after infarction, dichotomized as improved or not improved (that is, no change, decline in at least one category, or death).

RESULTS

Social class maintained its independent effect on improved functional status, even after controlling for pertinent prognostic factors. Persons of high social class were significantly more likely than persons of low or middle social class to have improved functional status 1 year after infarction. Certain clinical, demographic, and psychosocial features were related to recovery, but the effect of social class could not be explained by these additional features.

CONCLUSIONS

Social class has a substantial influence on recovery from myocardial infarction and may explain differences in clinical outcomes.

摘要

背景

社会阶层一直与心血管相关疾病及死亡存在关联,但尚无研究探讨社会阶层对心肌梗死后恢复情况的影响。此外,很少有研究同时评估一系列可能影响心肌梗死后健康结局的图形、临床和心理社会因素。

目的

确定即使在控制了已知会影响梗死后结局的临床、人口统计学和心理社会因素之后,社会阶层是否仍与心肌梗死后的功能恢复独立相关。

设计

对一项多中心、随机、双盲临床试验的前瞻性数据进行分析。

地点

美国和加拿大的25家医院或临床机构,这些机构参与了β受体阻滞剂心肌梗死试验,包括健康保险计划子研究。

患者

2145名年龄在29至69岁之间因急性心肌梗死住院并被纳入β受体阻滞剂心肌梗死试验的男性。

测量指标

主要结局是纽约心脏协会功能分级在基线评估和梗死后12个月之间的变化,分为改善或未改善(即无变化、至少下降一个等级或死亡)。

结果

即使在控制了相关预后因素之后,社会阶层对功能状态改善仍保持独立影响。社会阶层高的人在梗死后1年功能状态改善的可能性显著高于社会阶层低或中等的人。某些临床、人口统计学和心理社会特征与恢复有关,但社会阶层的影响无法用这些额外特征来解释。

结论

社会阶层对心肌梗死后的恢复有重大影响,可能解释临床结局的差异。

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