Hamers-Casterman C, Wittouck E, van der Loo W, Hamers R
J Immunogenet. 1979 Dec;6(6):373-81. doi: 10.1111/j.1744-313x.1979.tb00692.x.
A survey for constant region gamma-chain allotypes (de locus) was undertaken in different lagomorph genera. As yet only Pronolagus rupestris, a paleolaginae, showed the presence of a determinant similar to rabbit d12 although it lacked the widespread e15 determinant. All seven individuals possessed the d12 like determinant which was studied by immunodiffusion, haemagglutination inhibition, radiobinding and binding inhibition assays. In addition, a new enzymic method for typing for d12, based on the presence of the asymmetric rabbit hinge carbohydrate linked to the d12 characteristic threonine, is presented. This method suggests, however, that, unlike the d12 rabbit, Pronolagus does not seem to have a majority of IgG molecules with a glycosylated hinge.
对不同兔形目属动物的恒定区γ链同种异型（de位点）进行了一项调查。到目前为止，只有古兔亚科的岩兔表现出存在一种类似于兔d12的决定簇，尽管它缺乏广泛存在的e15决定簇。所有七只个体都拥有类似d12的决定簇，通过免疫扩散、血凝抑制、放射结合和结合抑制试验对其进行了研究。此外，还提出了一种基于与d12特征性苏氨酸相连的不对称兔铰链碳水化合物的存在来对d12进行分型的新酶法。然而，该方法表明，与d12兔不同，岩兔似乎没有大多数带有糖基化铰链的IgG分子。
