Szaflarski N, Hanson C W
Adult Critical Care Nurse Practitioner Program, University of Pennsylvania School of Medicine, Philadelphia, USA.
AACN Clin Issues. 1997 Aug;8(3):481-96. doi: 10.1097/00044067-199708000-00016.
Metabolic acidosis is a pathophysiologic state that is associated with serious morbidities and mortality. The diagnosis of metabolic acidosis is perplexing for novice and expert advanced practice nurses for many reasons. Its differential diagnosis is broad and includes common and rare, complex disease. The diagnosis of metabolic acidosis is also difficult because it is frequently associated with mixed, acid-base disorders. Its clinical manifestations are often nonspecific or subclinical, which means that its diagnosis is made from laboratory and other diagnostic tests. Timely diagnosis of metabolic acidosis is needed to institute appropriate therapy to avoid negative physiologic effects.
代谢性酸中毒是一种与严重发病率和死亡率相关的病理生理状态。由于多种原因，代谢性酸中毒的诊断对于新手和专家级高级实践护士来说都很棘手。其鉴别诊断范围广泛，包括常见和罕见的复杂疾病。代谢性酸中毒的诊断也很困难，因为它经常与混合性酸碱紊乱相关。其临床表现往往是非特异性的或亚临床的，这意味着其诊断是通过实验室检查和其他诊断测试得出的。需要及时诊断代谢性酸中毒以便采取适当的治疗措施，避免产生负面的生理影响。
