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用于寄生虫感染的DNA疫苗。

DNA vaccines for parasitic infections.

作者信息

Kalinna B H

机构信息

Molecular Parasitology Unit, Australian Centre for International and Tropical Health and Nutrition, Queensland Institute of Medical Research, Bancroft Centre, Brisbane, Australia.

出版信息

Immunol Cell Biol. 1997 Aug;75(4):370-5. doi: 10.1038/icb.1997.58.

Abstract

There has been a tremendous explosion in the area of DNA vaccine research over the last 4 years, particularly in relation to antiviral vaccines. This report discusses the development and application of this new technology with regard to parasitic infections. Progress has been made towards the development of a vaccine against malaria, cryptosporidiosis, leishmaniasis, toxoplasmosis and schistosomiasis. In the future, nucleic acid vaccines will be a useful tool to help control these and other parasitic infections.

摘要

在过去4年里,DNA疫苗研究领域出现了巨大的突破,尤其是在抗病毒疫苗方面。本报告讨论了这项新技术在寄生虫感染方面的开发和应用。在开发抗疟疾、隐孢子虫病、利什曼病、弓形虫病和血吸虫病疫苗方面已取得进展。未来,核酸疫苗将成为帮助控制这些及其他寄生虫感染的有用工具。

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