Lord B J, King M G, Pfister H P
J Comp Physiol Psychol. 1976 Mar;90(3):303-16. doi: 10.1037/h0088010.
Six experiments are reported on the effects of 2,4,5-trihydroxyphenylethyl-amine (6-hydroxydopamine) on two-way escape and avoidance learning. Rats were tested on either escape or avoidance learning at 80 days of age after chemical sympathectomy at birth or 40 or 80 days of age. Neonatal and chronic sympathectomy (at 40 days), but not acute sympathectomy (at 80 days), resulted in depressed escape learning. Avoidance learning was affected by neonatal sympathectomy and partially by acute sympathectomy. The results have implications for the role of the autonomic nervous system in escape-avoidance learning.
本文报告了六项关于2,4,5-三羟基苯乙胺（6-羟基多巴胺）对双向逃避和回避学习影响的实验。在出生时进行化学交感神经切除术后80日龄的大鼠，或40日龄或80日龄的大鼠，接受逃避或回避学习测试。新生期和慢性交感神经切除术（40日龄时），而非急性交感神经切除术（80日龄时），导致逃避学习能力下降。回避学习受到新生期交感神经切除术的影响，也部分受到急性交感神经切除术的影响。这些结果对自主神经系统在逃避-回避学习中的作用具有启示意义。
