Oei T P, King M G
J Comp Physiol Psychol. 1978 Feb;92(1):94-108. doi: 10.1037/h0077450.
Three experiments are reported on the relation among catecholamine (CA) depletion, plasma corticosterone (11-OHCS) levels, and active aversive learning. A baseline study showed no significant relation beteen resting levels of 11-OHCS and central and/or peripheral CA depletion. On a two-way avoidance learning task, depletion of brain CAs produced a widespread learning deficit. When both central and peripheral CAs were depleted, only escape learning emerged. Similar effects occurred on a one-way task, but differences were not so marked. The findings are discussed in terms of a theory of CA-dependent cues.
本文报道了三项关于儿茶酚胺（CA）耗竭、血浆皮质酮（11-羟基皮质类固醇，11-OHCS）水平与主动回避学习之间关系的实验。一项基线研究表明，11-OHCS的静息水平与中枢和/或外周CA耗竭之间无显著关系。在双向回避学习任务中，脑内CA的耗竭导致广泛的学习缺陷。当中枢和外周CA均被耗竭时，仅出现逃避学习。在单向任务中也出现了类似的效应，但差异不那么明显。本文根据CA依赖线索理论对这些发现进行了讨论。
