Hermans C, Straetmans N, Michaux J L, Ferrant A
Hematology Department, Cliniques Universitaires Saint-Luc, Catholic University of Louvain, Brussels, Belgium.
Ann Hematol. 1997 Jul-Aug;75(1-2):55-7. doi: 10.1007/s002770050312.
Pericarditis is a rare side effect of chemotherapy. We report here the case of a patient treated with high-dose cytosine arabinoside (HD ara-c) who developed severe pericarditis. Interruption of HD ara-c and initiation of corticosteroid treatment were effective in resolving the pericardial effusion. This case illustrates this rare but potentially life-threatening cardiac complication of HD ara-c therapy as well as the beneficial effect of corticosteroid treatment.
心包炎是化疗的一种罕见副作用。我们在此报告一例接受大剂量阿糖胞苷（HD ara-c）治疗的患者发生严重心包炎的病例。中断HD ara-c治疗并开始使用皮质类固醇治疗可有效消除心包积液。该病例说明了HD ara-c治疗这种罕见但可能危及生命的心脏并发症以及皮质类固醇治疗的有益效果。
