Liow R Y, Murray D W
Nuffield Department of Orthopaedic Surgery, University of Oxford.
Ann R Coll Surg Engl. 1997 Sep;79(5):335-40.
Comparative information on total knee replacements (TKRs) is not readily available. With the help of implant manufacturers and distributors, we have compiled a list of TKRs on the market in the UK and summarised the information about these implants in a table. There are 37 different TKRs, marketed by 14 companies; 54% have been introduced since 1990. The number of different implants is increasing. At least eight designs have undergone major modifications, while many have had minor alterations. Of the TKRs on the market, 60% are modular. Some 54% of TKRs have no published results in peer-reviewed journals; only one of the four most widely used prostheses has published survival figures. New and modified implants are introduced without clinical evidence of their superiority over other available designs. Published results in peer-reviewed journals are currently the best evidence available on the reliability of an implant. When selecting an implant, surgeons should be aware if the prosthesis has any such results, the length of the follow-up, and the survival rates that are achieved. More detailed interpretation is difficult because of the different combinations used in modular implants and because of the frequent modification of existing designs. Properly conducted long-term clinical trials should be encouraged as they are the only means of evaluating new designs.
关于全膝关节置换术(TKR)的对比信息并不容易获取。在植入物制造商和经销商的帮助下,我们编制了一份英国市场上TKR的清单,并将这些植入物的信息汇总在一张表格中。共有37种不同的TKR,由14家公司销售;其中54%是1990年以后推出的。不同植入物的数量在增加。至少有八种设计进行了重大修改,而许多则有小的改动。市场上的TKR中,60%是模块化的。约54%的TKR在同行评审期刊上没有发表结果;四种使用最广泛的假体中只有一种公布了生存率数据。新的和经过修改的植入物在没有临床证据证明其优于其他现有设计的情况下就被引入。同行评审期刊上发表的结果是目前关于植入物可靠性的最佳证据。在选择植入物时,外科医生应了解该假体是否有此类结果、随访时间长度以及所达到的生存率。由于模块化植入物使用的不同组合以及现有设计的频繁修改,更详细的解读很困难。应鼓励开展恰当的长期临床试验,因为这是评估新设计的唯一方法。