van der Horst C M, de Borgie C A, Knopper J L, Bossuyt P M
Department of Plastic and Reconstructive Surgery, University of Amsterdam, The Netherlands.
Br J Plast Surg. 1997 Sep;50(6):463-7. doi: 10.1016/s0007-1226(97)90335-0.
To assess the impact of a facial port wine stain (PWS) on behavioural problems in children and on health related quality of life in adults applying for laser treatment.
A survey by questionnaire of patients with PWS not previously treated.
Two standard general instruments and a more specific PWS questionnaire were used. Adolescents and adults (13-31 years) received a short version of the RAND Health Insurance Questionnaire from the Medical Outcome Study (MOS-24). Children's (4-12 years) parents received the Child Behaviour Checklist (CBCL). A specific PWS questionnaire was sent to both age groups.
The results of the MOS-24 were compared with those of a reference population without chronic illness. Observed behaviour in children was compared with data from a Dutch reference group, from children with constipation and from another group of children with a PWS.
41 MOS-24 and 41 CBCL were returned (91% and 95% response rates, respectively). Adolescents and adults reported little effect on role and social functioning, but showed low scores for mental health, self-perceived health and vitality/health. Children's parents reported no clinically significant problem behaviour (T-score > 70). Adults experienced more negative psychosocial consequences of having a PWS than children (specific PWS questionnaire).
Children with PWS do not show significant problem behaviour. Adolescents and adults reported less vitality/energy than was expected in this age group. Adolescents and adults showed statistically significant negative consequences of their PWS in social contacts compared to children (P < or = 0.01, Mann-Whitney).
评估面部葡萄酒色斑（PWS）对儿童行为问题以及对申请激光治疗的成年人健康相关生活质量的影响。
对既往未接受治疗的PWS患者进行问卷调查。
使用了两种标准通用工具和一份更具针对性的PWS问卷。青少年及成年人（13 - 31岁）接受了医学结局研究中的兰德健康保险简短问卷（MOS - 24）。儿童（4 - 12岁）的父母则收到儿童行为量表（CBCL）。向两个年龄组均发放了一份特定的PWS问卷。
将MOS - 24的结果与无慢性疾病的参照人群的结果进行比较。将观察到的儿童行为与来自荷兰参照组、便秘儿童组以及另一组患有PWS的儿童的数据进行比较。
共收回41份MOS - 24问卷和41份CBCL问卷（回复率分别为91%和95%）。青少年及成年人报告称对角色和社会功能影响较小，但心理健康、自我感知健康及活力/健康得分较低。儿童的父母报告未出现具有临床意义的问题行为（T分数>70）。成年人因患有PWS所经历的负面心理社会后果比儿童更多（特定的PWS问卷）。
患有PWS的儿童未表现出明显的问题行为。青少年及成年人报告的活力/精力低于该年龄组的预期水平。与儿童相比，青少年及成年人的PWS在社交接触方面显示出具有统计学意义的负面后果（P≤0.01，曼 - 惠特尼检验）。
