Wanitphakdeedecha Rungsima, Ng Janice Natasha C, Yan Chadakan, Manuskiatti Woraphong, Sudhipongpracha Tatchalerm, Jantarakolica Tatre
Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
College of Interdisciplinary Studies, Thammasat University, Bangkok, Thailand.
Clin Cosmet Investig Dermatol. 2021 Jun 22;14:681-690. doi: 10.2147/CCID.S315804. eCollection 2021.
Port-wine stain (PWS) is a congenital malformation that does not resolve spontaneously and can cause a physiological or psychological burden to the patients. At present, most of the studies done on PWS are focused on the treatment rather than the quality of life and psychological effects of the disease.
A comprehensive literature search was done in MEDLINE using PubMed database, Embase, and Cochrane. All observational studies were included in this review.
A total of 17 relevant articles with 2,135 PWS patients were included in this review. There were 36 measurement tools used to assess the quality of life and the psychological effects among PWS patients. The results showed that patients with facial PWS had a significant negative effect on their quality of life and had also suffered from psychological disabilities. The PWS lesion tends to worsen with age and may cause further adaptation problems towards the social environment, especially in children.
Early treatment, psychological assistance, and patient support are the key management in improving the quality of life of patients with PWS. Quality of life must be regularly assessed together with the improvement of treatment.
葡萄酒色斑（PWS）是一种先天性畸形，不会自行消退，会给患者带来生理或心理负担。目前，大多数关于PWS的研究都集中在治疗上，而非该疾病对生活质量和心理的影响。
使用PubMed数据库、Embase和Cochrane在MEDLINE中进行了全面的文献检索。本综述纳入了所有观察性研究。
本综述共纳入17篇相关文章，涉及2135例PWS患者。共有36种测量工具用于评估PWS患者的生活质量和心理影响。结果表明，面部患有PWS的患者对其生活质量有显著负面影响，并且还患有心理障碍。PWS病变往往会随着年龄增长而恶化，可能会导致对社会环境的进一步适应问题，尤其是在儿童中。
早期治疗、心理援助和患者支持是改善PWS患者生活质量的关键管理措施。必须定期评估生活质量，并同时改善治疗效果。
