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一项意外发现:治疗史与中国葡萄酒色斑患者的生活质量相关。

An Unexpected Finding: Treatment History Associated with the Quality of Life in Chinese Patients with Port-Wine Stains.

作者信息

Zhao Qian, Liu Lian, Li Xiaoxue, Yang Lihua, Jiang Xian

机构信息

Department of Dermatology, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.

Department of Medical Cosmetology, Chengdu Second People's Hospital, Chengdu, Sichuan, 610021, People's Republic of China.

出版信息

Clin Cosmet Investig Dermatol. 2023 Jul 27;16:1969-1975. doi: 10.2147/CCID.S421296. eCollection 2023.

DOI:10.2147/CCID.S421296
PMID:37533495
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10391529/
Abstract

BACKGROUND

Port-wine stains (PWS) are predominantly located on the face and neck. Hence, PWS affect not only aesthetic appearance but may also cause psychological distress. However, very few studies have researched on the quality of life (QoL) in Chinese patients with PWS.

AIM

To evaluate QoL in patients with PWS.

METHODS AND MATERIALS

Skindex-29 and Dermatology Life Quality Index (DLQI) were used to investigate the QoL of the patients with PWS and healthy controls.

RESULTS

In total, 198 adults with PWS and 200 healthy controls were included. The scores of symptomatic, emotional and functional dimensions of Skindex-29 in the observational group were significantly higher as compared with the control group (<0.05). Female gender, lesion location and the treatment history (such as pulsed dye laser or photodynamic therapy) had a negative impact on the scores (emotional and functional dimensions) of the patients with PWS. The median DLQI score was 3 points in the observational group and 0 points in the control group (<0.05), and QoL of patients who had a history of previous treatments was diminished.

CONCLUSION

The QoL of patients with PWS is impaired. Patients' QoL is negatively influenced by female gender, lesion location and treatment history. The Skindex-29 scale seems to be more applicable to the study of QoL of patients with PWS.

摘要

背景

葡萄酒色斑(PWS)主要位于面部和颈部。因此,PWS不仅影响美观,还可能导致心理困扰。然而,很少有研究针对中国PWS患者的生活质量(QoL)进行调查。

目的

评估PWS患者的生活质量。

方法和材料

使用Skindex-29和皮肤病生活质量指数(DLQI)对PWS患者和健康对照者的生活质量进行调查。

结果

总共纳入了198例成年PWS患者和200例健康对照者。观察组Skindex-29量表的症状、情感和功能维度得分显著高于对照组(<0.05)。女性性别、病变部位和治疗史(如脉冲染料激光或光动力疗法)对PWS患者的得分(情感和功能维度)有负面影响。观察组DLQI得分中位数为3分,对照组为0分(<0.05),既往有治疗史的患者生活质量下降。

结论

PWS患者的生活质量受损。患者的生活质量受到女性性别、病变部位和治疗史的负面影响。Skindex-29量表似乎更适用于PWS患者生活质量的研究。

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