Miller R F, Dacheux R F
J Gen Physiol. 1976 Jun;67(6):679-90. doi: 10.1085/jgp.67.6.679.
A chloride-free environment produces selective changes in the retinal network which include a separation of on and off channels. The identification of chloride-sensitive and insensitivie neuronal activity permits identification of some of the connections and intervening polarities of synaptic interactions which are expressed in ganglion cell receptive field organization. These experiments support previous suggestions that surround antagonism is dependent on horizontal cell activity. In addition they suggest a model of the neuronal connections which subserve on-center, off-center, and on-off ganglion cells. Experimental tests of the on-off ganglion cell model favor the idea that this type of ganglion cell receives inhibitory input from amacrine cells and excitatory activation from depolarizing and hyperpolarizing bipolar cells.
无氯离子环境会在视网膜网络中产生选择性变化，其中包括开通道和关通道的分离。对氯离子敏感和不敏感的神经元活动的识别，有助于确定一些突触相互作用的连接和中间极性，这些极性在神经节细胞感受野组织中有所体现。这些实验支持了之前关于周边拮抗作用依赖于水平细胞活动的观点。此外，它们还提出了一个关于神经节细胞连接的模型，该模型支持中心开、中心关和开-关神经节细胞。对开-关神经节细胞模型的实验测试支持了这样一种观点，即这种类型的神经节细胞接受来自无长突细胞的抑制性输入以及来自去极化和超极化双极细胞的兴奋性激活。
