Wamala S P, Wolk A, Schenck-Gustafsson K, Orth-Gomér K
National Institute for Psychosocial Factors and Health, Karolinska Institute, Stockholm, Sweden.
J Epidemiol Community Health. 1997 Aug;51(4):400-7. doi: 10.1136/jech.51.4.400.
To examine the relationship between socioeconomic status (SES) and full lipid profile in middle aged healthy women.
These comprised 300 healthy Swedish women between 30 and 65 years who constitute the control group of the Stockholm female coronary risk study, a population based, case-control study of women with coronary heart disease (CHD). The age matched control group, drawn from the census register of greater Stockholm, was representative of healthy Swedish women aged 30-65 years. Five measures of SES were used; educational level, occupation, decision latitude at work, annual income, and size of house or apartment.
Swedish women with low decision latitude at work, low income, low educational level, blue collar jobs, and who were living in small houses or apartments had an unhealthy lipid profile, suggesting an increased risk of CHD. Part of this social gradient in lipids was explained by an unhealthy lifestyle, but the lipid gradients associated with decision latitude at work and annual income were independent of these factors. Decision latitude, educational level, and annual income had the strongest associations with lipid profile. These associations were independent of age, menopausal status, smoking, sedentary lifestyle, alcohol consumption, obesity, excess abdominal fat, and unhealthy dietary habits. Of the lipid variables, low high density lipoprotein cholesterol (HDL) levels were most consistently associated with low SES.
Decision latitude at work was the strongest SES predictor of HDL levels in healthy middle aged Swedish women, after simultaneous adjustment for other SES measures, age, and all lifestyle factors in the multivariable regression model.
探讨中年健康女性的社会经济地位(SES)与完整血脂谱之间的关系。
这些参与者包括300名年龄在30至65岁之间的健康瑞典女性,她们构成了斯德哥尔摩女性冠心病风险研究的对照组,该研究是一项基于人群的冠心病(CHD)女性病例对照研究。从大斯德哥尔摩人口普查登记册中选取的年龄匹配对照组代表了30至65岁的健康瑞典女性。使用了五种SES衡量指标:教育水平、职业、工作中的决策自由度、年收入以及房屋或公寓面积。
工作中决策自由度低、收入低、教育水平低、从事蓝领工作且居住在小房子或公寓里的瑞典女性血脂谱不健康,提示患冠心病的风险增加。这种血脂方面的社会梯度部分可由不健康的生活方式解释,但与工作决策自由度和年收入相关的血脂梯度独立于这些因素。决策自由度、教育水平和年收入与血脂谱的关联最强。这些关联独立于年龄、绝经状态、吸烟、久坐不动的生活方式、饮酒、肥胖、腹部脂肪过多以及不健康的饮食习惯。在血脂变量中,低高密度脂蛋白胆固醇(HDL)水平与低SES最一致相关。
在多变量回归模型中同时调整其他SES指标、年龄和所有生活方式因素后,工作中的决策自由度是健康中年瑞典女性HDL水平最强的SES预测因素。