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豚鼠羊膜转运与通透性特性的研究。

A study of the transport and permeability properties of the guinea-pig amniotic membrane.

作者信息

North P M, Segal M B

出版信息

J Physiol. 1976 Mar;256(1):245-56. doi: 10.1113/jphysiol.1976.sp011323.

Abstract
  1. The simultaneous measurement of the two-way sodium flux across the in vitro amniotic epithelium did not reveal a preferential active movement of sodium in either direction. The amnion is thus unlikely to be the site of formation of amniotic fluid. 2. The permeability of the amniotic epithelium to some non-electrolytes has been measured with isotopes and was found to be generally low in relation to the thinness of the tissue. The permeability to non-electroytes would appear to be depebility to sodium and to non-electrolytes was found to vary with gestational age. The amnion from animals of 61-70 days' gestation was markedly more permanent than those at 50-60 days (term 70 days).
摘要
  1. 对体外羊膜上皮细胞双向钠通量的同步测量未显示出钠在任一方向上有优先的主动转运。因此,羊膜不太可能是羊水形成的部位。2. 已用同位素测量了羊膜上皮细胞对某些非电解质的通透性,发现相对于组织的薄度而言,其通透性总体较低。对非电解质的通透性似乎取决于对钠的通透性,并且发现对非电解质的通透性随胎龄而变化。妊娠61 - 70天动物的羊膜比妊娠50 - 60天(足月为70天)的羊膜通透性明显更低。

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