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整合素与外向信号转导：蛋白激酶C和磷脂酰肌醇-3,4,5-三磷酸的汇聚信号

Integrins and inside-out signal transduction: converging signals from PKC and PIP3.

作者信息

Kolanus W, Seed B

机构信息

Laboratorium für Molekulare Biologie, Genzentrum der Universität München, Germany.

出版信息

Curr Opin Cell Biol. 1997 Oct;9(5):725-31. doi: 10.1016/s0955-0674(97)80127-5.

DOI:10.1016/s0955-0674(97)80127-5
PMID:9330877
Abstract

Recent studies have identified molecules that interact with integrins and appear to participate in the signaling pathways that regulate integrin adhesiveness. Clues provided by studies of these molecules point to the integration by integrins of signal transduction pathways implicated in cell division and activation.

摘要

最近的研究已经鉴定出与整联蛋白相互作用且似乎参与调节整联蛋白黏附性的信号通路的分子。对这些分子的研究所提供的线索表明，整联蛋白参与了与细胞分裂和激活相关的信号转导通路的整合。

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