Csekeö A, Agócs L, Egerváry M
Országos Korányi Tbc és Pulmonológiai Intézet, Budapest.
Orv Hetil. 1997 Sep 7;138(36):2219-21.
Between 1983 and 1996., 79 patients'--operated on for pulmonary aspergilloma--clinical data has been analysed. The patients were comprised of 67 males and 12 females, with a mean age of 49 years (range, 24 to 69). Previous lung disorders were observed in about half of the cases (most frequently tuberculosis), while in the other half aspergilloma was developed on the basis of (sub)-acute infections. The most common symptom was haemoptysis (in 45% of cases). Aspergilloma was diagnosed preoperatively (especially by typical chest x-ray) in 62 patients. In the other cases tb, lung cancer, pyosclerosis were suspected. 67 patients underwent pulmonary resection (50 lobectomies, 12 wedge resections, 5 pneumonectomies), 12 cavities were opened by cavernostomy. The postoperative mortality rate was 10.1%. The most frequent complications were bleeding, prolonged air leak, pleural rest space, empyema, bronchial fistula and wound infection, which were occurred in cases with bigger cavities near chest wall. In most cases with pulmonary aspergilloma surgery remains the only effective treatment. Operation has a lower risk in asymptomatic patients, without chest wall involvement. In several cases cavernostomy might be applied successfully.
1983年至1996年间,对79例因肺曲菌球接受手术治疗患者的临床资料进行了分析。患者包括67名男性和12名女性,平均年龄49岁(范围24至69岁)。约半数病例既往有肺部疾病(最常见的是肺结核),而另一半病例中曲菌球是在(亚)急性感染基础上形成的。最常见的症状是咯血(45%的病例)。62例患者术前确诊为曲菌球(尤其是通过典型的胸部X线检查)。其他病例怀疑为肺结核、肺癌、硬化性肺炎。67例患者接受了肺切除术(50例肺叶切除术、12例楔形切除术、5例全肺切除术),12例通过空洞造口术打开空洞。术后死亡率为10.1%。最常见的并发症是出血、持续性漏气、胸膜残腔、脓胸、支气管瘘和伤口感染,这些并发症发生在靠近胸壁的较大空洞病例中。在大多数肺曲菌球病例中,手术仍然是唯一有效的治疗方法。对于无症状且无胸壁受累的患者,手术风险较低。在一些病例中,空洞造口术可能会成功应用。