Bang-Vojdanovski B, Träger D, Siebert W
Orthopädische Klinik Kassel.
Z Orthop Ihre Grenzgeb. 1997 May-Jun;135(3):252-7. doi: 10.1055/s-2008-1039589.
The risks associated with blood transfusion can be minimized using autologous blood. The efficiency of preoperative blood deposit, preoperative acute-hemodilution spinal anesthesia, controlled hypotension and intra and postoperative autotransfusion in reducing homologous transfusion has been demonstrated. In a prospective study the effectivity of this concept is demonstrated. 141 patients scheduled for total hip arthroplasty were divided in three groups: group I--total hip arthroplasty without cement (n = 55); group II--total hip arthroplasty with cement (n = 52); and group III total hip revision arthroplasty (n = 34). The mean quantity of the donated blood was 900 mL. The donation was not associated with serious complications. In group I 52 patients (94.5%), in group II 40 patients (77%) and in group III 14 patients (41.2%) did not require homologous transfusion. The difference between group I and II was significant (p < 0.05). Under the conditions studied, preoperative autologous blood deposit, acute hemodilution, spinal anesthesia and controlled hypotension are effective for decreasing the application of homologous transfusions in hip arthroplasty. The efficiency of preoperative hemodilution alone is limited. Preoperative deposit of autologous blood is a simple, effective, economical, and low-risk method of reducing homologous transfusion. Autotransfusion with a cell separator can save approximately 50% of the erythrocytes lost during revision total hip arthroplasty.
使用自体血可将输血相关风险降至最低。术前预存自体血、术前急性等容血液稀释联合脊髓麻醉、控制性低血压以及术中及术后自体输血在减少异体输血方面的有效性已得到证实。一项前瞻性研究证实了这一理念的有效性。141例计划行全髋关节置换术的患者被分为三组:第一组——非骨水泥型全髋关节置换术(n = 55);第二组——骨水泥型全髋关节置换术(n = 52);第三组——全髋关节翻修术(n = 34)。捐献血液的平均量为900 mL。献血未引发严重并发症。第一组52例患者(94.5%)、第二组40例患者(77%)以及第三组14例患者(41.2%)无需异体输血。第一组和第二组之间的差异具有统计学意义(p < 0.05)。在所研究的条件下,术前自体血预存、急性血液稀释、脊髓麻醉和控制性低血压对于减少髋关节置换术中异体输血的应用是有效的。单纯术前血液稀释的效果有限。术前自体血预存是一种简单、有效、经济且低风险的减少异体输血的方法。使用血细胞分离机进行自体输血可节省翻修全髋关节置换术中约50%丢失的红细胞。