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[铅中毒:临床表现、诊断及相关环境因素]

[Lead poisoning: clinical picture, diagnosis and related environmental factors].

作者信息

García R, Ghiringhelli M, Bachmann M

机构信息

Servicio de Medicina Interna, Hospital Naval (VM), Chile.

出版信息

Rev Med Chil. 1996 Dec;124(12):1476-82.

PMID:9334482
Abstract

BACKGROUND

The predisposing environmental factors and clinical picture of lead poisoning, are not well known.

AIM

To describe the clinical picture, diagnosis and treatment of lead poisoning in individuals under industry exposure.

SUBJECTS AND METHODS

Twenty of 38 workers of a printing press were studied. Their medical and labor histories were recorded. Lead in air in the working area and the dose received by the workers was measured.

RESULTS

The environmental lead in the linotype room was 25% over the accepted values. Twelve of the 20 workers were poisoned and three were highly exposed. Poisoned workers were working in areas with high environmental lead concentrations, were in direct contact with the metal, had plasma lead concentrations over 70 micrograms/dl and an average exposure time of over 17 years. Their clinical picture was not specific and related to plasma and environmental lead concentrations, length of exposure and type of contact.

CONCLUSIONS

Lead poisoning must be suspected among workers exposed to high environmental concentrations and its treatment consists in withdrawing poisoned subjects from polluted areas.

摘要

背景

铅中毒的诱发环境因素和临床表现尚不为人所知。

目的

描述职业接触铅的个体中铅中毒的临床表现、诊断和治疗。

对象与方法

对一家印刷厂38名工人中的20名进行了研究。记录他们的病史和工作史。测量了工作区域空气中的铅含量以及工人接触的铅剂量。

结果

铸排机房的环境铅含量超过公认值25%。20名工人中有12人中毒,3人接触程度高。中毒工人工作在环境铅浓度高的区域,直接接触金属,血浆铅浓度超过70微克/分升,平均接触时间超过17年。他们的临床表现不具有特异性,与血浆和环境铅浓度、接触时间长短及接触类型有关。

结论

接触高环境浓度铅的工人必须怀疑有铅中毒,其治疗方法是将中毒者撤离污染区域。

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