Parwaresch M R, Haacke H, Mäder C, Godt C
Klin Wochenschr. 1976 May 15;54(10):495-7. doi: 10.1007/BF01469052.
In 60 patients with corneal arcus the incidence of hyperlipoproteinemia was examined by serum lipid and lipoprotein analysis. An elevation of the serum lipid, or lipoprotein contents was found in every patient. 52 patients showed a primary type II hyperlipoproteinemia, three had a type IV, and one a type V pattern. In three cases hyperlipoproteinemia was found to be secondary to a severe cholestasis. The results show that the occurrence of corneal arcus in nearly every subject under 50 years of age and in most subjects over 50 years of age is highly suggestive of the presence of type II hyperlipoproteinemia. Until atherosclerotic complications appear, the course of the type II hyperlipoproteinemia is lingering and shows poor symptoms. Therefore, corneal arcus is of special importance for the early detection of this type of hyperlipoproteinemia.
对60例角膜弓患者进行血清脂质和脂蛋白分析，以检测高脂血症的发生率。发现每位患者的血清脂质或脂蛋白含量均升高。52例患者表现为原发性II型高脂血症，3例为IV型，1例为V型。3例高脂血症被发现继发于严重胆汁淤积。结果表明，几乎所有50岁以下及大多数50岁以上受试者出现角膜弓，高度提示存在II型高脂血症。在出现动脉粥样硬化并发症之前，II型高脂血症病程迁延，症状不明显。因此，角膜弓对于早期发现此类高脂血症具有特殊重要性。
