HrpA，一种新的核糖体相关蛋白，出现在热应激的卡介苗（牛分枝杆菌卡介苗）中。
HrpA, a new ribosome-associated protein which appears in heat-stressed Mycobacterium bovis bacillus Calmette-Guérin.
作者信息
Ohara N, Ohara N, Naito M, Miyazaki C, Matsumoto S, Tabira Y, Yamada T
机构信息
Nagasaki University School of Dentistry, Nagasaki City, Japan.
出版信息
J Bacteriol. 1997 Oct;179(20):6495-8. doi: 10.1128/jb.179.20.6495-6498.1997.
Abstract
A novel 18-kDa heat shock protein, HrpA, has been identified from Mycobacterium bovis BCG. HrpA was rapidly synthesized in membrane and ribosome fractions but not in the cytoplasmic fraction under heat shock stress. HrpA bound tightly to 70S ribosomes, mainly in 30S subunits. HrpA might be involved in the initiation step of translation at high temperature.
摘要
一种新的18 kDa热休克蛋白HrpA已从卡介苗中鉴定出来。在热休克应激下，HrpA在膜和核糖体组分中快速合成，但在细胞质组分中不合成。HrpA与70S核糖体紧密结合，主要存在于30S亚基中。HrpA可能参与高温下的翻译起始步骤。
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