在英国，非洲加勒比裔人群中精神病发病率的上升并非由于过多的妊娠和分娩并发症。

Increased rate of psychosis among African-Caribbeans in Britain is not due to an excess of pregnancy and birth complications.

作者信息

Hutchinson G, Takei N, Bhugra D, Fahy T A, Gilvarry C, Mallett R, Moran P, Leff J, Murray R M

机构信息

Department of Psychological Medicine, Institute of Psychiatry, London.

出版信息

Br J Psychiatry. 1997 Aug;171:145-7. doi: 10.1192/bjp.171.2.145.

DOI:10.1192/bjp.171.2.145

PMID:9337950

Abstract

BACKGROUND

It has been suggested that the increased rate of psychotic illness among African-Caribbeans living in Britain is due to an excess of pregnancy and birth complications (PBCs).

METHOD

We therefore compared the frequency of PBCs in a group of White psychotic patients (n = 103) and a comparable group of patients of African-Caribbean origin (n = 61); the latter consisted of 30 first-generation (born in the Caribbean) and 31 second-generation (born in Britain) individuals.

RESULTS

White psychotic patients were more than twice as likely to have a history of PBCs as their African-Caribbean counterparts (odds ratio = 2.34, 95% confidence interval (CI) 0.88-6.47, P = 0.062). The same trend was observed among patients with a DSM-III diagnosis of schizophrenia (odds ratio = 1.65, 95% CI 0.56-4.97, P = 0.32). The rate of PBCs was similar among the first- and second-generation Caribbean psychotic patients.

CONCLUSIONS

The increased rate of psychotic illness that has been reported among the African-Caribbean population in Britain is not due to an increased prevalence of PBCs.

摘要

背景

有观点认为，生活在英国的非洲裔加勒比人中精神疾病发病率上升是由于妊娠和分娩并发症（PBC）过多所致。

方法

因此，我们比较了一组白人精神病患者（n = 103）和一组与之匹配的非洲裔加勒比裔患者（n = 61）中PBC的发生频率；后者包括30名第一代（出生在加勒比地区）和31名第二代（出生在英国）个体。

结果

白人精神病患者有PBC病史的可能性是非洲裔加勒比裔患者的两倍多（优势比 = 2.34，95%置信区间（CI）0.88 - 6.47，P = 0.062）。在诊断为精神分裂症的DSM-III患者中也观察到了相同趋势（优势比 = 1.65，95% CI 0.56 - 4.97，P = 0.32）。第一代和第二代加勒比裔精神病患者的PBC发生率相似。