Crilley J G, Herd B, Khurana C S, Appleby C A, de Belder M A, Davies A, Hall J A
Department of Cardiology, South Cleveland Hospital, Middlesbrough, UK.
Postgrad Med J. 1997 Jul;73(861):415-8. doi: 10.1136/pgmj.73.861.415.
The study was designed to assess the outcome of treatment with permanent dual-chamber pacing of elderly patients with falls, dizziness and syncope associated with the demonstration of a hypersensitive cardioinhibitory reflex. Questionnaires were sent to patients (and their general practitioners) who had been referred to a regional pacing centre with recurrent falls, dizziness or syncope diagnosed as likely to be secondary to cardioinhibitory carotid sinus syndrome or predominantly cardioinhibitory vasovagal syndrome. After pacemaker insertion, 84% of patients had no further syncope over a mean follow-up period of 10 (range 1.5 to 30) months. Minor symptoms persisted in only 40% of all patients. Symptoms were unchanged in 22%. It was concluded that permanent dual-chamber pacing is an effective treatment for elderly patients with recurrent falls, dizziness and syncope in whom a hypersensitive cardioinhibitory reflex is found. Good results were obtained in this group with a simple diagnostic work-up.
本研究旨在评估对伴有跌倒、头晕和晕厥且存在心脏抑制反射过敏的老年患者进行永久性双腔起搏治疗的效果。研究向那些因反复跌倒、头晕或晕厥而被转诊至地区起搏中心，且诊断为可能继发于心脏抑制性颈动脉窦综合征或主要为心脏抑制性血管迷走神经综合征的患者（及其全科医生）发放了调查问卷。在植入起搏器后，平均随访10个月（范围为1.5至30个月），84%的患者未再出现晕厥。仅有40%的患者仍存在轻微症状。22%的患者症状未改变。研究得出结论，对于发现存在心脏抑制反射过敏的反复跌倒、头晕和晕厥的老年患者，永久性双腔起搏是一种有效的治疗方法。通过简单的诊断检查，该组患者取得了良好的治疗效果。
