Ashton C M, Del Junco D J, Souchek J, Wray N P, Mansyur C L
Center for Quality of Care and Utilization Studies, Veterans Affairs Medical Center, Houston, TX 77030, USA.
Med Care. 1997 Oct;35(10):1044-59. doi: 10.1097/00005650-199710000-00006.
To help resolve the current controversy over the validity of early readmission as an indicator of the quality of care, the authors critically reviewed the literature using meta-analysis to derive summary estimates of effect and evaluate inter-study heterogeneity.
The authors selected reports meeting five criteria: (1) presentation of new data on medical-surgical hospitalization of adults; (2) measurement of outcome as a person-specific readmission; (3) readmission within < or = 31 days; (4) examination of some aspect of the process of inpatient care; (5) inclusion of a comparison group. One meta-analysis examined 13 comparisons of readmission rates after substandard versus normative care, another examined 9 comparisons of readmission rates after normative versus exceptional care, and the third examined all 22 comparisons together. Two authors applied inclusion criteria and extracted data on methods and findings. Two others classified studies on 11 methodological variables for the heterogeneity evaluation.
The summary odds ratio for readmission after substandard care was 1.24 (0.99-1.57) relative to normative care; for readmission after normative care the summary odds ratio was 1.45 (0.90-2.33) relative to exceptional care. The individual odds ratios varied significantly (chi2, 21 df = 50.34, P = 0.0003). Most of the variance in study odds ratios could be explained by whether the study focused on the quality of patient care or the qualifications of patient care providers. The summary odds ratio for the 16 homogeneous comparisons focusing on the quality of patient care was 1.55 (1.25-1.92).
Early readmission is significantly associated with the process of inpatient care. The risk of early readmission is increased by 55% when care is of relatively low quality, that is, substandard or normative instead of normative or exceptional.
为帮助解决当前关于早期再入院作为医疗质量指标有效性的争议,作者通过荟萃分析对文献进行了批判性回顾,以得出效应的汇总估计值并评估研究间的异质性。
作者选择了符合五条标准的报告:(1)呈现关于成人内科 - 外科住院治疗的新数据;(2)将结局衡量为个体特异性再入院;(3)再入院时间在≤31天内;(4)检查住院护理过程的某些方面;(5)纳入一个对照组。一项荟萃分析考察了13项关于不合格护理与规范护理后再入院率的比较,另一项考察了9项关于规范护理与优质护理后再入院率的比较,第三项则一起考察了所有22项比较。两名作者应用纳入标准并提取了关于方法和研究结果的数据。另外两名作者根据11个方法学变量对研究进行分类以评估异质性。
与规范护理相比,不合格护理后再入院的汇总比值比为1.24(0.99 - 1.57);与优质护理相比,规范护理后再入院的汇总比值比为1.45(0.90 - 2.33)。个体比值比差异显著(卡方检验,自由度为21,χ² = 50.34,P = 0.0003)。研究比值比的大部分变异可由研究是关注患者护理质量还是患者护理提供者资质来解释。聚焦于患者护理质量的16项同质比较的汇总比值比为1.55(1.25 - 1.92)。
早期再入院与住院护理过程显著相关。当护理质量相对较低,即不合格或规范而非规范或优质时,早期再入院风险增加55%。