球状蛋白质中的结构模式。
Structural patterns in globular proteins.
作者信息
Levitt M, Chothia C
出版信息
Nature. 1976 Jun 17;261(5561):552-8. doi: 10.1038/261552a0.
DOI:10.1038/261552a0
PMID:934293
Abstract
A simple diagrammatic representation has been used to show the arrangement of alpha helices and beta sheets in 31 globular proteins, which are classified into four clearly separated classes. The observed arrangements are significantly non-random in that pieces of secondary structure adjacent in sequence along the polypeptide chain are also often in contact in three dimensions.
摘要
已使用一种简单的图示来展示31种球状蛋白质中α螺旋和β折叠的排列方式，这些蛋白质被分为四个明显不同的类别。观察到的排列方式具有显著的非随机性，即沿着多肽链序列相邻的二级结构片段在三维空间中也常常相互接触。
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