Saba P R, McDonald K, Hunn J, Dastur K, Chablani V
Department of Radiology, Mercy Hospital of Pittsburgh, PA 15219, USA.
Clin Nucl Med. 1997 Oct;22(10):679-82. doi: 10.1097/00003072-199710000-00003.
The authors present a case in which Tc-99m HMPAO labeled autologous leukocytes were used to demonstrate a brain abscess in a patient undergoing evaluation for fever of unknown origin. The abscess was demonstrated on both 1-hour and 24-hour images. The positive 1-hour image led to CT and MRI studies, which are included for correlation. In addition to its previously identified role as a secondary diagnostic test in the differentiation of tumor and abscess, the authors propose that Tc-99m HMPAO is useful as a primary diagnostic tool in the identification of brain abscess. Furthermore, the authors suggest that Tc-99m HMPAO is preferable to In-111 labeled leukocytes because of its better resolution and earlier imaging characteristics.
作者介绍了一个病例，其中使用锝-99m六甲基丙二胺肟（Tc-99m HMPAO）标记的自体白细胞来显示一名正在接受不明原因发热评估的患者的脑脓肿。在1小时和24小时的影像上均显示出脓肿。1小时的阳性影像促使进行了CT和MRI检查，本文将其列入以供对比。除了其先前确定的作为鉴别肿瘤和脓肿的二级诊断测试的作用外，作者提出Tc-99m HMPAO在识别脑脓肿方面可作为主要诊断工具。此外，作者认为由于Tc-99m HMPAO具有更好的分辨率和更早的成像特性，因此它比铟-111（In-111）标记的白细胞更具优势。
