Sartori E, Bazzurini L, Gadducci A, Landoni F, Lissoni A, Maggino T, Zola P, La Face B
Department of Obstetrics and Gynecology, University of Brescia, Italy.
Gynecol Oncol. 1997 Oct;67(1):70-5. doi: 10.1006/gyno.1997.4827.
The purpose of this paper is to retrospectively analyze the clinical and pathological data of 118 cases of uterine carcinosarcoma. Prognostic factors and management were evaluated. chi 2 and log-rank tests were performed. Surgical stage at time of surgery was the most important prognostic factor (P < 0.0001); in stage I-II disease depth of myometrial invasion and lymphatic/vascular space involvement were significantly related to outcome, whereas other factors were not useful. In stage I-II patients postoperative radiation did not improve 5-year disease-free survival. Survival curves in patients with advanced disease treated with cisplatin-containing regimens or with doxorubicin (without cisplatin)-containing regimens were overlapping.
本文旨在回顾性分析118例子宫癌肉瘤患者的临床和病理数据。评估预后因素并探讨治疗方法。进行了卡方检验和对数秩检验。手术时的手术分期是最重要的预后因素（P < 0.0001）；在Ⅰ-Ⅱ期疾病中，肌层浸润深度和淋巴/血管间隙受累与预后显著相关，而其他因素则无意义。在Ⅰ-Ⅱ期患者中，术后放疗并未改善5年无病生存率。接受含顺铂方案或含阿霉素（不含顺铂）方案治疗的晚期疾病患者的生存曲线相互重叠。
