Goncharov B F, Burzava-Zherar E, Fonten N A
Ontogenez. 1976;7(1):85-9.
A comparison was made of the biological effect of purified gonadotropins of the sevryuga and the carp on the activation of adenyl cyclase in the homogenate of the goldfish ovary, the reaction of spermiation in two species of frogs, and the in vitro maturation of oocytes of two amphibian species and sevryuga. The ratio of specific activities of the preparations under study was shown to vary markedly with respect to test-subject and test-reaction. The data obtained suggest, thus, qualitative differences in the effect of the gonadotropins under study and the response of organs-targets. It is proposed to use the system of in vitro maturation of amphibian oocytes for studying the phenomenon of species specificity of gonadotropins of lower vertebrates.
对塞弗里uga鱼和鲤鱼的纯化促性腺激素对金鱼卵巢匀浆中腺苷酸环化酶激活、两种蛙类的排精反应以及两种两栖类和塞弗里uga鱼卵母细胞体外成熟的生物学效应进行了比较。结果表明,所研究制剂的比活性比值因受试对象和测试反应的不同而有显著差异。因此,所获得的数据表明,所研究的促性腺激素的作用以及靶器官的反应存在质的差异。建议利用两栖类卵母细胞体外成熟系统来研究低等脊椎动物促性腺激素的物种特异性现象。