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一种由牛促黄体生成素α亚基和硬骨鱼促性腺激素一个亚基组成的、在青蛙中具有促性腺活性的分子杂交体。

[A molecular hybrid having gonadotropic activity in frogs composed of the alpha subunit of bovine luteinizing hormone and a subunit of a gonadotropin of a teleost fish].

作者信息

Fontaine M M

出版信息

C R Acad Hebd Seances Acad Sci D. 1976 Jan 5;282(1):97-100.

PMID:816536
Abstract

The alpha subunit of bovine LH and the subunit SU II of carp gonadotropin are able to associate. The hybrid is about one hundred times less active than c-GTH or b-LH, respectively on goldfish and rat ovarian adenyl cyclase. However it is more efficient than both horomones on an Amphibian (Rana esculenta), on spermiation in vivo as well as on ovarian adenyl cyclase in vitro.

摘要

牛促黄体激素的α亚基与鲤鱼促性腺激素的SU II亚基能够结合。该杂种在金鱼和大鼠卵巢腺苷酸环化酶上的活性分别比鲤鱼促性腺激素(c-GTH)或牛促黄体激素(b-LH)低约一百倍。然而,在两栖动物(食用蛙)上,无论是在体内诱导排精还是体外卵巢腺苷酸环化酶实验中,它都比这两种激素更有效。

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