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腰椎痛风性关节病:一例病例报告及文献复习

Gouty arthropathy of the lumbar spine: a case report and review of the literature.

作者信息

King J C, Nicholas C

机构信息

Kalamazoo Center for Medical Studies, Michigan State University, 49008, USA.

出版信息

Spine (Phila Pa 1976). 1997 Oct 1;22(19):2309-12. doi: 10.1097/00007632-199710010-00023.

Abstract

STUDY DESIGN

A patient with hyperuricemia developed symptoms from lateral recess stenosis attributed to gouty arthropathy of a lumbar facet joint.

OBJECTIVE

To present the diagnosis and management of gouty arthropathy of the lumbar spine in one individual.

SUMMARY OF BACKGROUND DATA

The symptoms and treatment of a patient with intra-articular gout of a lumbar facet are presented and contrasted with other cases of spinal extra-articular gout found in the literature.

METHODS

A patient with hyperuricemia reported back pain and symptoms consistent with lateral recess stenosis. Conservative treatment failed, and, after further evaluation, a successful decompressive laminectomy was performed. Pathology revealed intra-articular urate crystal deposition.

RESULTS

This patient's unilateral S1 radiculopathy corresponded with magnetic resonance and computed tomography studies documenting unilateral lateral L5-S1 lateral recess stenosis secondary to intra-articular gouty arthropathy. As anticipated, the serum uric acid also was elevated. Since surgical decompression with unilateral laminotomy was performed, the patient has been symptom-free for 2 years.

CONCLUSION

Although rare, gouty arthropathy of the lumbar facet joint should be considered in all patients with neurologic symptoms and known or suspected gout. Optimization of pharmacologic treatment is indicated for patients suspected of having gouty neuropathy. Surgical decompression is indicated if conservative management with Indocin, nonsteroidal anti-inflammatory agents, and allopurinol fails to reverse neurologic dysfunction.

摘要

研究设计

一名高尿酸血症患者出现了因腰椎小关节痛风性关节炎导致的侧隐窝狭窄症状。

目的

介绍一名个体腰椎痛风性关节炎的诊断和治疗。

背景资料总结

介绍了一名腰椎小关节内痛风患者的症状和治疗,并与文献中其他脊柱关节外痛风病例进行了对比。

方法

一名高尿酸血症患者报告有背痛及与侧隐窝狭窄相符的症状。保守治疗失败,经进一步评估后,成功实施了减压性椎板切除术。病理检查显示关节内尿酸盐结晶沉积。

结果

该患者的单侧S1神经根病与磁共振成像和计算机断层扫描结果相符,这些检查记录了因关节内痛风性关节炎继发的单侧L5 - S1侧隐窝狭窄。正如预期的那样,血清尿酸也升高。由于实施了单侧椎板切开减压手术,患者已无症状2年。

结论

尽管罕见,但对于所有有神经症状且已知或疑似痛风的患者,均应考虑腰椎小关节痛风性关节炎。对于疑似痛风性神经病变的患者,应优化药物治疗。如果使用消炎痛、非甾体抗炎药和别嘌呤醇进行保守治疗未能逆转神经功能障碍,则应进行手术减压。

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